
Flights
Flights from Madrid to Istanbul
Compare live fares from Madrid to Istanbul and book in a few steps.
Recent fares from Madrid to Istanbul
Airlines that fly nonstop from Madrid to Istanbul
Air EuropaMAD to ISTLast seen November 5, 2026
PegasusMAD to SAWLast seen November 4, 2026
Turkish AirlinesMAD to ISTLast seen November 5, 2026
Where to stay in Istanbul
Compare hotel prices in Istanbul and book your stay with the same account.
Questions about flights from Madrid to Istanbul
Yes. In the last 30 days, our searches found nonstop flights on this route with Air Europa, Pegasus, and Turkish Airlines.
On most airlines you can pick your seat on the plane map and add bags during checkout, with every price shown before you pay.